Estimulação transcraniana por corrente contínua na reabilitação do zumbido: relatos de casos
Transcranial direct current stimulation in tinnitus rehabilitation: a case report
Tássya Kamila Fernandes Caldas de Lima; Lidiane Maria de Brito Macedo Ferreira; Edgard Morya; Marine Raquel Diniz da Rosa; Erika Barioni Mantello
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Abstract
Tinnitus is an auditory perception without an external sound source. Transcranial direct current stimulation is a promising therapy for modulating the neurobiological substrates associated with this condition. This case report aimed to evaluate whether the discomfort and impact of tinnitus on patients' quality of life change after neuromodulation intervention. Adults with chronic tinnitus were included after otorhinolaryngological evaluation. The cases analyzed derive from a pilot study. The procedures included a speech-language-hearing history, pure-tone audiometry, high-frequency audiometry, pitch and loudness matching, a visual analog scale, and the Tinnitus Handicap Inventory. The intervention consisted of applying a 2-mA current for 20 min for 5 consecutive days, with an anodal electrode in the left temporoparietal area and a cathodal electrode in the right dorsolateral prefrontal cortex. The cases were expressed individually, and the data were analyzed descriptively. Five patients (three women and two men), with a mean age of 45 years, were evaluated. As to audiometry, six ears had normal hearing, while all ears had decreased high-frequency sensitivity. Scale scores decreased after five neuromodulation sessions; the mean score in the pre-therapy group decreased from 5.2 to 4.4 points post-therapy. The total questionnaire score decreased from 36.8 to 33.2 points. The mean loudness decreased from 10.4 to 9.2 dB SL. The results suggest that noninvasive neuromodulation reduced the annoyance and impact of tinnitus on these patients’ quality of life.
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Referências
1 Jarach CM, Lugo A, Scala M, van den Brandt PA, Cederroth CR, Odone A, et al. Global prevalence and incidence of tinnitus. JAMA Neurol. 2022;79(9):888-900.
2 Yang T, Zhang J, Wang B, Zhang W, Xu M, Yang S, et al. Electrical stimulation to treat tinnitus: a meta-analysis and systemic review of randomized controlled trials. Ther Adv Chronic Dis. 2021;12:1-21.
3 Bedaque HP, Silveira YB, Silva PHM, Ferreira LMBM. Prevalence of otological symptoms at Rio Grande do Norte’s population. Journal of Surgical and Clinical Research. 2023;14(1):12-20.
4 De Ridder D, Schlee W, Vanneste S, Londero A, Weisz N, Kleinjung T, et al. Tinnitus and tinnitus disorder: theoretical and operational definitions (an international multidisciplinary proposal). Prog Brain Res. 2021;260:1-25.
5 Mondelli MFCG, Rosa MRD. Zumbido e intervenções disponíveis. In: Schochat E, Samelli AG, Couto CM, Teixeira AR, Durante AS, Zanchetta S, editors. Tratado de audiologia. 3a ed. São Paulo: Manole; 2022. p. 676-85.
6 Cima RFF, Mazurek B, Haider H, Kikidis D, Lapira A, Noreña A, et al. A multidisciplinary European guideline for tinnitus: diagnostics, assessment, and treatment. HNO. 2019;67(S1, Suppl 1):10-42.
7 Suzuki FB, Teixeira AR. Testes audiológicos complementares para a investigação do zumbido, alterações cocleares e retrococleares. In: Schochat E, Samelli AG, Couto CM, Teixeira AR, Durante AS, Zanchetta S, editors. Tratado de audiologia. 3a ed. São Paulo: Manole; 2022. p. 112-24.
8 Martins ML, Souza DS, Cavalcante MEOB, Barboza HN, Medeiros JF, Andrade SMMS, et al. Effect of transcranial Direct Current Stimulation for tinnitus treatment: a systematic review and meta-analysis. Clin Neurophysiol. 2022;52(1):1-16.
9 Chen S, Du M, Wang Y, Li Y, Tong B, Qiu J, et al. State of the art: non-invasive electrical stimulation for the treatment of chronic tinnitus. Ther Adv Chronic Dis. 2023;14:20406223221148061.
10 Lee HY. Adjunctive role of bifrontal transcranial direct current stimulation in distressed patients with severe tinnitus. J Korean Med Sci. 2019;34(3):e19.
11 Moossavi A, Najaf S. Transcranial direct current stimulation in treatment of tinnitus. Auditory and Vestibular Research. 2021;30(1):1-8.
12 Peng F, Xiang Y, Xu H, Yin Q, Li J, Zou Y. Systematic review and meta-analysis of extended high-frequency audiometry in tinnitus patients. Ann Palliat Med. 2021;10(12):12129-39.
13 Souza DD, Almeida AA, Andrade SMS, Machado DGS, Leitão M, Sanchez TG, et al. Transcranial direct current stimulation improves tinnitus perception and modulates cortical electrical activity in patients with tinnitus: a randomized clinical trial. Clin Neurophysiol. 2020;50(4):289-300.
14 Nascimento ID, Almeida AA, Diniz J, Martins ML, Freitas TMMWC, Rosa MRD. Tinnitus evaluation: relationship between pitch matching and loudness, visual analog scale and tinnitus handicap inventory. Braz J Otorhinolaryngol. 2019;85(5):611-6.
Submetido em:
16/01/2025
Aceito em:
06/09/2025
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