Audiology - Communication Research
https://www.audiolcommres.org.br/article/doi/10.1590/2317-6431-2024-2999pt
Audiology - Communication Research
Original Article

Caracterização do Mismatch Negativity em crianças, adolescentes e adultos jovens

Characterization of Mismatch Negativity in children, adolescents and young adults

Laura Flach Schwade; Viviann Magalhães Silva Borges; Paulo Ricardo Gazzola Zen; Pricila Sleifer

http://dx.doi.org/10.1590/2317-6431-2024-2999pt Audiol. Commun. Res., vol.31, e2999, 2026
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Resumo

Objetivo: descrever e analisar as latências e amplitudes do Mismatch Negativity entre orelhas, sexos e faixa etária de crianças, adolescentes e adultos jovens.
Métodos: estudo transversal, do qual os participantes eram normo-ouvintes e com desenvolvimento típico, de ambos os sexos, sendo 260 crianças com idade entre 9 anos e 11 anos e 11 meses, 106 adolescentes entre 12 anos e 17 anos e 11 meses e 110 adultos jovens, entre 18 anos e 29 anos e 11 meses. Todos os sujeitos realizaram avaliação audiológica periférica (meatoscopia, medidas de imitância acústica, audiometria tonal limiar, audiometria vocal) e avaliação audiológica central (Potencial Evocado Auditivo de Tronco Encefálico e Mismatch Negativity).
Resultados: Verificou-se correlação negativa de latências do Mismatch Negativity para a variável faixa etária, diminuídas à medida que houve aumento da idade dos sujeitos avaliados. Não foi constatada diferença significativa de amplitudes do Mismatch Negativity em relação à faixa etária, assim como nas latências e amplitudes entre as orelhas e os sexos.
Conclusão: foi possível descrever as latências e amplitudes do Mismatch Negativity em crianças, adolescentes e adultos jovens. Verificou-se regressão de latências do Mismatch Negativity com o aumento da idade dos participantes.

Palavras-chave

Audição; Potenciais evocados auditivos; Criança; Adolescente; Adulto

Abstract

Purpose: To describe and analyze the latencies and amplitudes of mismatch negativity (MMN) according to ear, sex, and age group in children, adolescents, and young adults.

Methods: This cross-sectional study included participants with normal hearing and typical development of both sexes. The sample comprised 260 children aged 9 to 11 years and 11 months, 110 adolescents aged 12 to 17 years and 11 months, and 110 young adults aged 18 to 29 years and 11 months. All participants underwent peripheral audiological assessment (otoscopy, acoustic immittance measures, pure-tone audiometry, and speech audiometry) and central auditory evaluation (brainstem auditory evoked potentials and mismatch negativity).

Results: A negative correlation was observed between MMN latency and age group, indicating a decrease in latency with increasing age. No significant differences were found in MMN amplitudes across age groups, nor in MMN latencies and amplitudes between ears or sexes.

Conclusion: The latencies and amplitudes of mismatch negativity were characterized in children, adolescents, and young adults. A reduction in MMN latency was observed with increasing age.

Keywords

Hearing; Evoked potentials; Auditory; Child; Adolescent; Adult

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Submitted date:
10/24/2024

Accepted date:
11/05/2025

699f002da953955ffc461715 acr Articles
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